In the last decade, scientific studies in the field of children's gastroenterology performed in Lithuania explored different problems:pathology of Helicobacter plori infection and food allergy. Our studies revealed that children with atopic dermatitis had gastrointestinal complaints (abdominal pain, diarrhea, distension and unstable stool, which appeared with the exacerbation of skin rash)more often as compared to nonallergic children of the control group. Abdominal pain in children with atopic dermatitis with local rash was more frequent and lasted longer than in control group children, whereas children with extended rash had stools more frequently.
Gastrointestinal disorders in children with atopic dermatitis statistically significantly did not depend on the extent of skin rash and severity of atopic dermatitis. In our scientific research on the importance of H. pylori infection on children's gastrointestinal system,children with chronic dyspepsia were examined. Endoscopу,rapid urease test,biopsies from antrum and corpus of stomach and their histological examination as well as serologic tests were done. According to the results obtained, we recommend to examine children with chronic dyspepsia in a complex way: not only endoscopic examination. but H. pylori diagnostic tests should be performed as well. Serologic test is not suitable for screening H. pylori infection in children. Considering this, we recommend to use no fewer than two different methods to diagnose this infection. The highest frequency of H. pylori infection was found in children with duodenal ulcer;histological changes in their gastric pylorus and corpus mucosa were greatest. More than half of children with nonulcer dyspepsia were infected with H.pylori. After eradication of H. pylori infection, the prevalence of dyspepsia in children with duodenal ulcer decreased.
參考譯文
過去10年里，立陶宛在小兒胃腸病學(xué)領(lǐng)域?qū)Χ鄠€課題進(jìn)行了研究和探索：幽門螺旋桿菌感染和食物過敏的病理學(xué)。我們的研究揭示：特異性皮炎患兒的胃腸道癥狀(腹痛、腹瀉、腹脹、排便習(xí)慣紊亂這些現(xiàn)象的發(fā)生，伴隨皮疹的惡化)比對照組非過敏性兒童頻發(fā)?；继禺愋云ぱ装榫窒扌云ふ畹幕純罕葘φ战M兒童腹痛發(fā)生頻率高而且持續(xù)時間長，全身性皮疹的患兒的排便癥狀則更為頻繁。
特異性皮炎患兒中胃腸道紊亂的發(fā)生并不取決于皮疹的范圍和特異性皮炎的嚴(yán)重程度，這點具有統(tǒng)計學(xué)意義。我們對幽門螺旋桿菌感染對小兒胃腸系統(tǒng)重要性進(jìn)行了科學(xué)研究，對慢性消化不良的惠兒給予內(nèi)鏡檢測、快速尿素酶檢測、胃竇和胃體活檢、組織學(xué)檢測和血清學(xué)測試等檢查。根據(jù)所獲結(jié)果,我們推薦對慢性消化不良的患兒進(jìn)行復(fù)合檢查:不僅需要進(jìn)行內(nèi)鏡檢查，還應(yīng)進(jìn)行幽門螺旋桿菌診斷性檢測。血清學(xué)檢測不適合篩查兒童幽門螺旋桿菌感染。因此，我們推薦使用至少兩種方法來診斷幽門螺旋桿菌的感染。在十二指腸潰瘍的患兒中幽門螺旋桿菌的檢出率最高，幽門部和胃體黏膜的組織學(xué)改變也最大。超過一半的非潰瘍性消化不良患兒有幽門螺旋桿菌感染。當(dāng)幽門螺旋桿菌根除之后，十二指腸潰瘍患兒中的消化不良癥狀的發(fā)生率就會降低。
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