Title: Sudden death in hypertrophic myocardiopathy

標(biāo)題：肥厚性心肌病性猝死

Content/內(nèi)容：

1) Hypertrophic cardiomyopathy is the most common cause of sudden death in young individuals who are otherwise healthy.

肥厚性心肌病是無其他疾患的青年人中最常見的猝死原因。

2) Risk of sudden death is highest in patients who are between 14 and 35 years old.

14~35歲患者的猝死危險(xiǎn)度最高。

3) Several mechanisms are involved in sudden death: ventricular arrhythmias, supraventricular arrhythmias leading to cardiac collapse. bradycardias and severe ischemia.

猝死涉及以下機(jī)制：室性心律失常、室上性心律失常導(dǎo)致心源性休克、心動(dòng)過緩及重度心肌缺血。

4) The factors that best identify high risk patients are: previous history of sudden death or syncope, induction in adults of sustained ventricular arrhythmias, the presence of non-sustained ventricular tachycardia in symptomatic patients, the presence of ischemia associated with hypotension in children, the presence of mutations in the beta-myosin heavy chain together with a family history of sudden death and a poor left ventricular ejection fraction.

有助于識(shí)別高危病人的最佳因素有猝死或暈厥過去病史、成人誘發(fā)持續(xù)性室性心律失常、有癥狀病人出現(xiàn)非持續(xù)性室性心動(dòng)過速、患兒出現(xiàn)低血醫(yī)相關(guān)心肌缺血、出現(xiàn)β肌漿球蛋白重鏈突變伴猝死家族史以及左心室射血分?jǐn)?shù)不佳。

5) Risk stratification should be done on an individualized basis.

危險(xiǎn)度分層分析應(yīng)根據(jù)個(gè)人具體情況而行。

6) In those patients in whom a high risk for sudden arrhythmic death is suspected, the only current effective treatment is the implantable defibrillator.

對(duì)于心律失常性猝死高?；颊?，當(dāng)前唯一有效治療是植入去顫器。

責(zé)任編輯：admin